In a collaborative effort with Heather Clark's Nanosensors lab at Northeastern University (Boston), we have recently published a review on in vivo biosensing in the new ACS Sensors journal. The article focuses on several case studies in which dynamic monitoring has been investigated in pre-clinical animal studies, finding only several groups world-wide who have actually demonstrated true dynamic monitoring inside organisms. Furthermore, we highlighted recent advances in scaffold materials (e.g. neural monitoring with materials designed to be biocompatible) and biological receptors that could open up new opportunities for monitoring proteins and cells (aptamers, engineered proteins), rather than ions and metabolites.